Ontology highlight
ABSTRACT:
INSTRUMENT(S): esquire 6000
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Daniela Cecconi
LAB HEAD: Daniela Cecconi
PROVIDER: PXD000119 | Pride | 2014-07-10
REPOSITORIES: Pride
Electrophoresis 20130411 9-10
The pancreatic adenocarcinoma cell line Panc1 was treated with cannabinoid receptor ligands (arachidonylcyclopropylamide or GW405833) in order to elucidate the molecular mechanism of their anticancer effect. A proteomic approach was used to analyze the protein and phosphoprotein profiles. Western blot and functional data mining were also employed in order to validate results, classify proteins, and explore their potential relationships. We demonstrated that the two cannabinoids act through a wid ...[more]