Proteomics

Dataset Information

0

Panorama of ancient metazoan macromolecular complexes: Human, Cell paper 2012: MOCK


ABSTRACT: By combining extensive biochemical fractionation with quantitative mass spectrometry, we directly examined the composition of soluble multiprotein complexes among diverse animal models. The project has been jointly supervised by Andrew Emili and Edward M. Marcotte. Project website: http://metazoa.med.utoronto.ca

INSTRUMENT(S): LTQ Orbitrap Velos, LTQ XL

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Blake borgeson  

LAB HEAD: Andrew Emili

PROVIDER: PXD002328 | Pride | 2016-05-18

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
5_8cyto01.MSGFDB_out Other
5_8cyto01.RAW Raw
5_8cyto01.inspect_out Other
Hs.fasta Fasta
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Publications


Macromolecular complexes are essential to conserved biological processes, but their prevalence across animals is unclear. By combining extensive biochemical fractionation with quantitative mass spectrometry, here we directly examined the composition of soluble multiprotein complexes among diverse metazoan models. Using an integrative approach, we generated a draft conservation map consisting of more than one million putative high-confidence co-complex interactions for species with fully sequence  ...[more]

Publication: 1/2

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