Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Cricetulus Griseus (chinese Hamster) (cricetulus Barabensis Griseus)
TISSUE(S): Permanent Cell Line Cell
SUBMITTER: Pekka Rappu
LAB HEAD: Jyrki Heino
PROVIDER: PXD003153 | Pride | 2016-07-11
REPOSITORIES: Pride
Action | DRS | |||
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130306Pekka_Export_peptide_norm2all.csv | Csv | |||
130306Pekka_Export_protein_norm2all.csv | Csv | |||
130306_PekkaR_EtOH1.raw | Raw | |||
130306_PekkaR_EtOH2.raw | Raw | |||
130306_PekkaR_EtOH3.raw | Raw |
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Salmela Maria M Rappu Pekka P Lilja Johanna J Niskanen Henri H Taipalus Elina E Jokinen Johanna J Heino Jyrki J
The international journal of biochemistry & cell biology 20160629
Phorbol diester PMA (phorbol 12-myristate 13-acetate) is a well-known promoter of tumor progression. PMA also regulates cell adhesion by several mechanisms including conformational activation of integrins and integrin clustering. Here, PMA was shown to induce lamellipodia formation and reorganization of the adhesion sites as well as actin and vimentin filaments independently of integrin preactivation. To further analyze the mechanism of PMA action, the protein composition in the α1β1 integrin/co ...[more]