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The comparative proteomics research of Toxoplasma infection in mice liver

ABSTRACT: The comparative proteomics research of Toxoplasma infection in mice liver

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Hepatocyte, Liver

DISEASE(S): Mixed Disorder As Reaction To Stress

SUBMITTER: Junjun He

LAB HEAD: Xingquan zhu

PROVIDER: PXD003399 | Pride | 2016-03-31

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	MouseToxo_all.dat	Other
	mouse_1.mgf	Mgf
	mouse_1.wiff	Wiff
	mouse_1.wiff.scan	Wiff
	mouse_10.mgf	Mgf

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Publications

Proteomic Profiling of Mouse Liver following Acute Toxoplasma gondii Infection.

He Jun-Jun JJ Ma Jun J Elsheikha Hany M HM Song Hui-Qun HQ Zhou Dong-Hui DH Zhu Xing-Quan XQ

PloS one 20160322 3

Toxoplasma gondii remains a global public health problem. However, its pathophysiology is still not-completely understood particularly the impact of infection on host liver metabolism. We performed iTRAQ-based proteomic analysis to evaluate early liver protein responses in BALB/c mice following infection with T. gondii PYS strain (genotype ToxoDB#9) infection. Our data revealed modification of protein expression in key metabolic pathways, as indicated by the upregulation of immune response and d ...[more]

PMID: 27003162

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