Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Cell, Blood
DISEASE(S): Acute Leukemia
SUBMITTER: Sander Piersma
LAB HEAD: Connie Ramona Jimenez
PROVIDER: PXD007237 | Pride | 2019-11-11
REPOSITORIES: Pride
Items per page: 1 - 5 of 39 |
The Journal of biological chemistry 20170919 49
<i>Trypanosoma brucei</i> causes African trypanosomiasis and contains three full-length oligosaccharyltransferase (OST) genes; two of which, <i>Tb</i>STT3A and <i>Tb</i>STT3B, are expressed in the bloodstream form of the parasite. These OSTs have different peptide acceptor and lipid-linked oligosaccharide donor specificities, and trypanosomes do not follow many of the canonical rules developed for other eukaryotic <i>N</i>-glycosylation pathways, raising questions as to the basic architecture an ...[more]