Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Cell Line Cell
DISEASE(S): Lung Cancer,Colon Cancer,Acute Leukemia,Prostate Cancer,Brain Cancer,Kidney Cancer,Malignant Neoplasm Of Ovary,Breast Cancer
SUBMITTER: Tiannan Guo
LAB HEAD: Ruedi Aebersold
PROVIDER: PXD009597 | Pride | 2019-10-21
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
consensus.splib | Other | |||
guot_J130320_001.wiff | Wiff | |||
guot_J130320_001.wiff.scan | Wiff | |||
guot_J130320_002.wiff | Wiff | |||
guot_J130320_002.wiff.scan | Wiff |
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Guo Tiannan T Luna Augustin A Rajapakse Vinodh N VN Koh Ching Chiek CC Wu Zhicheng Z Liu Wei W Sun Yaoting Y Gao Huanhuan H Menden Michael P MP Xu Chao C Calzone Laurence L Martignetti Loredana L Auwerx Chiara C Buljan Marija M Banaei-Esfahani Amir A Ori Alessandro A Iskar Murat M Gillet Ludovic L Bi Ran R Zhang Jiangnan J Zhang Huanhuan H Yu Chenhuan C Zhong Qing Q Varma Sudhir S Schmitt Uwe U Qiu Peng P Zhang Qiushi Q Zhu Yi Y Wild Peter J PJ Garnett Mathew J MJ Bork Peer P Beck Martin M Liu Kexin K Saez-Rodriguez Julio J Elloumi Fathi F Reinhold William C WC Sander Chris C Pommier Yves Y Aebersold Ruedi R
iScience 20191031
Here we describe a proteomic data resource for the NCI-60 cell lines generated by pressure cycling technology and SWATH mass spectrometry. We developed the DIA-expert software to curate and visualize the SWATH data, leading to reproducible detection of over 3,100 SwissProt proteotypic proteins and systematic quantification of pathway activities. Stoichiometric relationships of interacting proteins for DNA replication, repair, the chromatin remodeling NuRD complex, β-catenin, RNA metabolism, and ...[more]