Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Ludovic Gillet
LAB HEAD: Ruedi A Aebersold
PROVIDER: PXD016320 | Pride | 2021-06-28
REPOSITORIES: Pride
Items per page: 1 - 5 of 30 |
Nature communications 20210804 1
Productive ribosomal RNA (rRNA) compaction during ribosome assembly necessitates establishing correct tertiary contacts between distant secondary structure elements. Here, we quantify the response of the yeast proteome to low temperature (LT), a condition where aberrant mis-paired RNA folding intermediates accumulate. We show that, at LT, yeast cells globally boost production of their ribosome assembly machinery. We find that the LT-induced assembly factor, Puf6, binds to the nascent catalytic R ...[more]