Proteomics

Dataset Information

0

Yeast proteomic analysis upon temperature shift


ABSTRACT: DIA/SWATH analysis of yeast upon temperature shift.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: Ludovic Gillet  

LAB HEAD: Ruedi A Aebersold

PROVIDER: PXD016320 | Pride | 2021-06-28

REPOSITORIES: Pride

Dataset's files

Source:
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Publications


Productive ribosomal RNA (rRNA) compaction during ribosome assembly necessitates establishing correct tertiary contacts between distant secondary structure elements. Here, we quantify the response of the yeast proteome to low temperature (LT), a condition where aberrant mis-paired RNA folding intermediates accumulate. We show that, at LT, yeast cells globally boost production of their ribosome assembly machinery. We find that the LT-induced assembly factor, Puf6, binds to the nascent catalytic R  ...[more]

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