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Enterococcus faecalis V583, Part 1

ABSTRACT: Genome-scale models represent the link between an organism's genetic information and experimentally observable biological phenotypes. They facilitate metabolic engineering and the discovery of network properties such as the identification of novel drug targets. Most commonly, metabolite consumption data is used to limit the solution space, sometimes in combination with gene expression data. However, information about gene expression only poorly correlates with the abundance of the respective proteins within the cell. As such, we developed a method to map and integrate the whole-cell proteome into genome-scale models on the example of lactic acid bacteria (LAB). To the best of our knowledge, this work represents the first effort to integrate proteome data into genome-scale models on such a scale.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Enterococcus Faecalis (streptococcus Faecalis)

TISSUE(S): Cell

SUBMITTER: Ben Collins

LAB HEAD: Ursula Kummer

PROVIDER: PXD001576 | Pride | 2016-12-06

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	efv583_iRT_cons_6trs_decoy_openswath_protfdr4_140603.TraML	Other
	efv583_iRT_cons_6trs_decoy_openswath_protfdr4_140603.csv	Csv
	feature_alignment.tsv	Tabular
	guot_L131214_001.mzXML	Mzxml
	guot_L131214_002.mzXML	Mzxml

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