Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brain
SUBMITTER: Monika Zareba-Koziol
LAB HEAD: Jakub M Wlodarczyk
PROVIDER: PXD010822 | Pride | 2019-07-16
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
509292309zar_PAL_K1_s.dat | Other | |||
509292309zar_PAL_K1_s.raw | Raw | |||
509292310zar_PAL_K2_s.dat | Other | |||
509292310zar_PAL_K2_s.raw | Raw | |||
509292311zar_PAL_K3_s.dat | Other |
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Molecular & cellular proteomics : MCP 20190716 10
The precise regulation of synaptic integrity is critical for neuronal network connectivity and proper brain function. Essential aspects of the activity and localization of synaptic proteins are regulated by posttranslational modifications. S-palmitoylation is a reversible covalent modification of the cysteine with palmitate. It modulates affinity of the protein for cell membranes and membranous compartments. Intracellular palmitoylation dynamics are regulated by crosstalk with other posttranslat ...[more]