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Human macrophages in 3D - Macrophages are involved in a large number of tissue functions in homeostasis and various pathological situations

ABSTRACT: Macrophages are involved in a large number of tissue functions in homeostasis and various pathological situations. These cells present a high degree of phenotypic plasticity that is grasped by the concept of polarization. One goal of the macrophage’s biology field is to obtain molecular signatures of these polarizations. To achieve this task, it is necessary to integrate how physical environment signals are interpreted by macrophages under immune stimulation. In this work, we have studied how a 3D collagen scaffold modulates the polarizations of human macrophages and revealed that some traditionally used markers should be reassessed.

INSTRUMENT(S): maXis

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood, Macrophage

DISEASE(S): Wounds And Injuries

SUBMITTER: Arnaud Millet

LAB HEAD: MILLET Arnaud

PROVIDER: PXD012147 | Pride | 2019-04-18

REPOSITORIES: Pride

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			Action	DRS
	M1_2D_13072016_R1.7z	Other
	M1_2D_13072016_R2.7z	Other
	M1_2D_13072016_R3.7z	Other
	M1_2D_15062016_R1.7z	Other
	M1_2D_15062016_R2.7z	Other

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