Proteomics

Dataset Information

0

Proteomic effects of mIR-877-3p in cervical cancer


ABSTRACT: A subcellular proteomic workflow was carried out with three biological replicates in each experimental condition, using MOCK, NC- and anti-miR-877-transfections in C-33A and SiHa cells.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Uterine Cervix

DISEASE(S): Cervix Carcinoma

SUBMITTER: Enrique Santamaría  

LAB HEAD: Enrique Santamaria

PROVIDER: PXD014993 | Pride | 2021-09-08

REPOSITORIES: Pride

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Publications


No therapeutic targets and molecular biomarkers are available in cervical cancer (CC) management. In other cancer types, micro-RNA-877-3p (miR-877-3p) has been associated with events relevant for CC development. Thus, we aimed to determine miR-877-3p role in CC. miR-877-3p levels were examined by quantitative-PCR in 117 cervical lesions and tumors. Effects on CC cell proliferation, migration, and invasion were evaluated upon anti-miR-877-3p transfection. miR-877-3p dependent molecular mechanism  ...[more]

Publication: 1/2

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