Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Chlamydomonas Reinhardtii
SUBMITTER: Alexander Leitner
LAB HEAD: Takashi Ishikawa
PROVIDER: PXD015658 | Pride | 2020-08-07
REPOSITORIES: Pride
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Journal of cell science 20200821 16
The radial spoke is a key element in a transducer apparatus controlling the motility of eukaryotic cilia. The transduction biomechanics is a long-standing question in cilia biology. The radial spoke has three regions - a spoke head, a bifurcated neck and a stalk. Although the neck and the stalk are asymmetric, twofold symmetry of the head has remained controversial. In this work we used single particle cryo-electron microscopy (cryo-EM) analysis to generate a 3D structure of the whole radial spo ...[more]