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LC-MS/MS Data of Skeletal Muscle and Plasma of Preruminant Calves fed with Leucine and Threonine Supplemented Diets

ABSTRACT: The objective of present work is to use foodomics approaches in calves’ skeletal muscle and plasma to fully assess the effects of the supplementations of leucine and threonine in the MR during preweaning period (5.6 days to 53.6 days) under the hypothesis that AA supplementation will modify the energy metabolism, especially of the muscle tissue. This study extends our understanding on the metabolism in dairy calves and help to optimize their nutritional status.

OTHER RELATED OMICS DATASETS IN: MTBLS1045

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Blood Plasma, Muscle

DISEASE(S): Nutrition

SUBMITTER: Anita Horvatic

LAB HEAD: Peter David Eckersall

PROVIDER: PXD016098 | Pride | 2020-02-17

REPOSITORIES: Pride

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Metabolome and proteome changes in skeletal muscle and blood of pre-weaning calves fed leucine and threonine supplemented diets.

Yu Kuai K Matzapetakis Manolis M Horvatić Anita A Terré Marta M Bach Alex A Kuleš Josipa J Yeste Natalia N Gómez Néstor N Arroyo Laura L Rodríguez-Tomàs Elisabet E Peña Raquel R Guillemin Nicolas N de Almeida André M AM Eckersall Peter David PD Bassols Anna A

Journal of proteomics 20200203

In pre-weaning calves, both leucine and threonine play important roles in growth and muscle metabolism. In this study, metabolomics, proteomics and clinical chemistry were used to assess the effects of leucine and threonine supplementation added to milk replacer on 14 newborn Holstein male calves: 7 were fed a control diet (Ctrl) and 7 were fed the Ctrl diet supplemented with 0.3% leucine and 0.3% threonine (LT) from 5.6 days of age to 53.6 days. At this time, blood and semitendinosus muscle bio ...[more]

PMID: 32028040

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