Proteomics

Dataset Information

0

Hodgkin lymphoma-educated macrophages


ABSTRACT: Comparative proteome analysis of HL and DLBCL educated human macrophages by SWATH-MS.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Macrophage

DISEASE(S): Lymphoma

SUBMITTER: Katharina Limm  

LAB HEAD: Prof. Dr. Peter Oefner

PROVIDER: PXD016128 | Pride | 2020-01-29

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
180417P3-2018_11.wiff Wiff
180417P3-2018_11.wiff.scan Wiff
180417P3-2018_12.wiff Wiff
180417P3-2018_12.wiff.scan Wiff
180417P3-2018_13.wiff Wiff
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Publications


Macrophages (Mφ) are abundantly present in the tumor microenvironment and may predict outcome in solid tumors and defined lymphoma subtypes. Mφ heterogeneity, the mechanisms of their recruitment, and their differentiation into lymphoma-promoting, alternatively activated M2-like phenotypes are still not fully understood. Therefore, further functional studies are required to understand biological mechanisms associated with human tumor-associated Mφ (TAM). Here, we show that the global mRNA express  ...[more]

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