Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Macrophage
DISEASE(S): Lymphoma
SUBMITTER: Katharina Limm
LAB HEAD: Prof. Dr. Peter Oefner
PROVIDER: PXD016128 | Pride | 2020-01-29
REPOSITORIES: Pride
Action | DRS | |||
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180417P3-2018_11.wiff | Wiff | |||
180417P3-2018_11.wiff.scan | Wiff | |||
180417P3-2018_12.wiff | Wiff | |||
180417P3-2018_12.wiff.scan | Wiff | |||
180417P3-2018_13.wiff | Wiff |
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Arlt Annekatrin A von Bonin Frederike F Rehberg Thorsten T Perez-Rubio Paula P Engelmann Julia C JC Limm Katharina K Reinke Sarah S Dullin Christian C Sun Xueni X Specht Rieke R Maulhardt Markus M Linke Franziska F Bunt Gertrude G Klapper Wolfram W Vockerodt Martina M Wilting Jörg J Pukrop Tobias T Dettmer Katja K Gronwald Wolfram W Oefner Peter J PJ Spang Rainer R Kube Dieter D
Molecular oncology 20200128 3
Macrophages (Mφ) are abundantly present in the tumor microenvironment and may predict outcome in solid tumors and defined lymphoma subtypes. Mφ heterogeneity, the mechanisms of their recruitment, and their differentiation into lymphoma-promoting, alternatively activated M2-like phenotypes are still not fully understood. Therefore, further functional studies are required to understand biological mechanisms associated with human tumor-associated Mφ (TAM). Here, we show that the global mRNA express ...[more]