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Analysis of mouse glomerular cells

ABSTRACT: Protoemics of endothelia, podocytes, mesangial cells from mouse

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Kidney

SUBMITTER: Markus Rinschen

LAB HEAD: Markus Rinschen

PROVIDER: PXD016238 | Pride | 2022-06-09

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	20190626_Q1_AWH_ColID_837c_ProjID_1795_Benzing_sample_01.index	Other
	20190626_Q1_AWH_ColID_837c_ProjID_1795_Benzing_sample_01.raw	Raw
	20190626_Q1_AWH_ColID_837c_ProjID_1795_Benzing_sample_02.index	Other
	20190626_Q1_AWH_ColID_837c_ProjID_1795_Benzing_sample_02.raw	Raw
	20190626_Q1_AWH_ColID_837c_ProjID_1795_Benzing_sample_03.index	Other

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1 - 5 of 32

Publications

ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage.

Sachs Marlies M Wetzel Sebastian S Reichelt Julia J Sachs Wiebke W Schebsdat Lisa L Zielinski Stephanie S Seipold Lisa L Heintz Lukas L Müller Stephan A SA Kretz Oliver O Lindenmeyer Maja M Wiech Thorsten T Huber Tobias B TB Lüllmann-Rauch Renate R Lichtenthaler Stefan F SF Saftig Paul P Meyer-Schwesinger Catherine C

Journal of the American Society of Nephrology : JASN 20210330 6

<h4>Background</h4>Podocytes embrace the glomerular capillaries with foot processes, which are interconnected by a specialized adherens junction to ultimately form the filtration barrier. Altered adhesion and loss are common features of podocyte injury, which could be mediated by shedding of cell-adhesion molecules through the regulated activity of cell surface-expressed proteases. A Disintegrin and Metalloproteinase 10 (ADAM10) is such a protease known to mediate ectodomain shedding of adhesion ...[more]

PMID: 33785583

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