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Global Proteome Profiling of Human Fetal Nucleus Pulposus tissues

ABSTRACT: Intervertebral disc degeneration is accompanied by a loss of Extra-cellular matrix (ECM) content due to an imbalance in anabolic and catabolic pathways. Identifying ECM proteins with anabolic and/or regenerative potential could be the key to developing regenerative therapies. Since human fetal discs grow and develop very rapidly, studying these discs may provide valuable insights on proteins with regenerative potential. Hence, the aim of this explorative study is to identify proteins of interest for future therapies through profiling the global proteome of human fetal NP’s.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Nucleus Pulposus, Notochordal Cell

DISEASE(S): Degenerative Disc Disease

SUBMITTER: Chitraa Tangavel

LAB HEAD: Dr Chitraa Tangavel

PROVIDER: PXD016648 | Pride | 2025-01-07

REPOSITORIES: Pride

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			Action	DRS
	CT_T024_NP_S1_Pool1_1.mgf	Mgf
	CT_T024_NP_S1_Pool1_1.mzML	Mzml
	CT_T024_NP_S1_Pool1_1.mzid.gz	Mzid
	CT_T024_NP_S1_Pool1_1.pride.mgf.gz	Mgf
	CT_T024_NP_S1_Pool1_1.pride.mztab.gz	Mztab

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