Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
SUBMITTER: Bill Huang
LAB HEAD: Hee-Yong Kim
PROVIDER: PXD017128 | Pride | 2020-05-27
REPOSITORIES: pride
Action | DRS | |||
---|---|---|---|---|
DMSODSS-80-160.mgf | Mgf | |||
DMSODSS-80-160.mgf.xQuest.mgf | Mgf | |||
DMSODSS-80-160.raw | Raw | |||
DSS-C1.mgf | Mgf | |||
DSS-C1.mgf.xQuest.mgf | Mgf |
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Communications biology 20200306 1
Adhesion G protein-coupled receptors (aGPCR) are characterized by a large extracellular region containing a conserved GPCR-autoproteolysis-inducing (GAIN) domain. Despite their relevance to several disease conditions, we do not understand the molecular mechanism by which aGPCRs are physiologically activated. GPR110 (ADGRF1) was recently deorphanized as the functional receptor of N-docosahexaenoylethanolamine (synaptamide), a potent synaptogenic metabolite of docosahexaenoic acid. Thus far, synap ...[more]