Dataset Information

Proteomic characterization of damaged single hairs recovered after an explosion for protein-based human identification

ABSTRACT: Characterization of hair proteome in damaged single hairs after an explosive blast and evaluation of success rates in genetically variant peptide marker detection for protein-based human identification.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Keratinocyte

SUBMITTER: Fanny Chu

LAB HEAD: Deon S. Anex

PROVIDER: PXD017427 | Pride | 2020-05-14

REPOSITORIES: Pride

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Publications

Proteomic Characterization of Damaged Single Hairs Recovered after an Explosion for Protein-Based Human Identification.

Chu Fanny F Mason Katelyn E KE Anex Deon S DS Jones A Daniel AD Hart Bradley R BR

Journal of proteome research 20200604 8

Evidence recovery is challenging where an explosion has occurred. Though hair evidence may be sufficiently robust to be recovered at the site, forensic analysis underutilizes the matrix by relying on morphological analysis. Where DNA is compromised, particularly in hair, protein-based human identification presents a promising alternative. Detection of amino acid polymorphisms in hair proteins as genetically variant peptides (GVPs) permits the inference of individualizing single nucleotide polymo ...[more]

PMID: 32394717

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