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Adipocytes alter the ALL translational programme to enhance their dormancy and stress resistance.

ABSTRACT: We investigated the possibility that adipocyte mediated stress protection is accompanied by activation of a selective mRNA translation analogous to stress induced translational arrest. Nalm-6 cells were subjected at +24 and +48h under 3T3-L1 adipocyte co-culture to Pulsed Stable Isotope Chromatography-mass spectrometry (SILAC) based proteomic analysis to estimate protein translation rates over time relative to pre-adipocyte control conditions.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Cell Culture

DISEASE(S): Acute Leukemia

SUBMITTER: Faraz Mardakheh

LAB HEAD: Faraz Mardakheh

PROVIDER: PXD019369 | Pride | 2021-06-11

REPOSITORIES: Pride

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			Action	DRS
	QE2_190603_chrysi_sample24_fracD.raw	Raw
	QE2_190603_chrysi_sample24_fracE.raw	Raw
	QE2_190603_chrysi_sample24_fracF.raw	Raw
	QE2_190603_chrysi_sample24_fracGH.raw	Raw
	QE2_190603_chrysi_sample48_fracD.raw	Raw

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