Proteomics

Dataset Information

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Comparative proteomic profiling of 3T3-L1 adipocyte differentiation using SILAC quantification


ABSTRACT: Comparative proteomic profiling of 3T3-L1 adipocyte differentiation using SILAC quantification

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture, Fibroblast

DISEASE(S): Type 2 Diabetes Mellitus

SUBMITTER: Sunkyu Choi  

LAB HEAD: Sunkyu Choi

PROVIDER: PXD019716 | Pride | 2020-10-26

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
3T3_L1_SILAC_1_H_L_ACN10_1.raw Raw
3T3_L1_SILAC_1_H_L_ACN10_2.raw Raw
3T3_L1_SILAC_1_H_L_ACN10_3.raw Raw
3T3_L1_SILAC_1_H_L_ACN15_1.raw Raw
3T3_L1_SILAC_1_H_L_ACN15_2.raw Raw
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Publications

Comparative Proteomic Profiling of 3T3-L1 Adipocyte Differentiation Using SILAC Quantification.

Choi Sunkyu S   Goswami Neha N   Schmidt Frank F  

Journal of proteome research 20201008 12


Adipocyte differentiation is a general physiological process that is also critical for metabolic syndrome. In spite of extensive study in the past two decades, adipogenesis is a still complex cellular process that is accompanied by complicated molecular mechanisms. Here, we performed SILAC-based quantitative global proteomic profiling of 3T3-L1 adipocyte differentiation. We report protein changes to the proteome profiles, with 354 proteins exhibiting significant increase and 56 proteins showing  ...[more]

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