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The human GID complex engages two independent modules for substrate recruitment

ABSTRACT: Chemical cross-linking coupled to mass spectrometry was used to study two different assemblies of the human E3 ubiquitin ligase complex, GID. The 5mer complex consisted of subunits MAEA, RMND5a, TWA1, WDR26, and RanBP9; the 6mer complex consisted of the subunits of the 5mer complex and the additional subunit ARMC8β. Cross-linking experiments were performed with disuccinimidyl suberate (DSS) or pimelic dihydrazide (PDH) in combination with the coupling reagent DMTMM.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Alexander Leitner

LAB HEAD: Alexander Leitner

PROVIDER: PXD024822 | Pride | 2021-08-25

REPOSITORIES: Pride

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			Action	DRS
	210307_LU02_aleitner_hGID_01.raw	Raw
	210307_LU02_aleitner_hGID_02.raw	Raw
	210307_LU02_aleitner_hGID_03.raw	Raw
	210307_LU02_aleitner_hGID_04.raw	Raw
	210307_LU02_aleitner_hGID_05.raw	Raw

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