Dataset Information

BoxCar and Shotgun Proteomic Analyses Reveal Molecular Networks Regulated by UBR5 in Prostate Cancer

ABSTRACT: The project aims to compare BoxCar and shotgun proteomics in identifying proteins regulated by UBR5 in prostate cancer cells.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Prostate Adenocarcinoma

SUBMITTER: Wei Yang

LAB HEAD: Wei Yang

PROVIDER: PXD026382 | Pride | 2022-02-22

REPOSITORIES: pride

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BoxCar and shotgun proteomic analyses reveal molecular networks regulated by UBR5 in prostate cancer.

Yan Yiwu Y Zhou Bo B Lee Yeon-Joo YJ You Sungyong S Freeman Michael R MR Yang Wei W

Proteomics 20211223 4

Prostate cancer (PC) is a major health and economic problem in industrialized countries, yet our understanding of the molecular mechanisms of PC progression and drug response remains limited. Accumulating evidence showed that certain E3 ubiquitin ligases such as SIAH2, RNF7, and SPOP play important roles in PC development and progression. However, the roles and mechanisms of other E3s in PC progression remain largely unexplored. Through an integration analysis of clinical genomic and transcripto ...[more]

PMID: 34897998

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			Action	DRS
	Human20200424.fasta	Fasta
	Human20200424_additional.fasta	Fasta
	PC3_HCDFT_Fr01.raw	Raw
	PC3_HCDFT_Fr02.raw	Raw
	PC3_HCDFT_Fr03.raw	Raw