Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Podospora Anserina
SUBMITTER: Ilka Wittig
LAB HEAD: Heinz D. Osiewacz
PROVIDER: PXD029352 | Pride | 2022-02-22
REPOSITORIES: Pride
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P20_124_Osiewacz_WT_18d_01.raw | Raw | |||
P20_124_Osiewacz_WT_18d_02.raw | Raw | |||
P20_124_Osiewacz_WT_18d_03.raw | Raw | |||
P20_124_Osiewacz_WT_18d_04.raw | Raw |
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Cells 20211126 12
The accumulation of functionally impaired mitochondria is a key event in aging. Previous works with the fungal aging model <i>Podospora anserina</i> demonstrated pronounced age-dependent changes of mitochondrial morphology and ultrastructure, as well as alterations of transcript and protein levels, including individual proteins of the oxidative phosphorylation (OXPHOS). The identified protein changes do not reflect the level of the whole protein complexes as they function in-vivo. In the present ...[more]