Dataset Information
Pytheas S. cerevisiae 18S rRNA sample analysis
Ontology highlight
ABSTRACT:
INSTRUMENT(S): 6520A Quadrupole Time-of-Flight LC/MS
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: 
Luigi D'Ascenzo
LAB HEAD: James R. Williamson
PROVIDER: PXD030563 | Pride | 2022-05-04
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 18SRNA.rdn18.fasta | Fasta | |||
| 18S_yeast_56DU_N14N15_20pmol.mgf | Mgf | |||
| 80SRNAmodlist.txt | Txt | |||
| Digest_18S_yeast.txt | Txt | |||
| match_output_18S_yeast_56DU_N14N15_20pmol.txt | Txt |
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Publications
Pytheas: a software package for the automated analysis of RNA sequences and modifications via tandem mass spectrometry.
Nature communications 20220503 1
Mass spectrometry is an important method for analysis of modified nucleosides ubiquitously present in cellular RNAs, in particular for ribosomal and transfer RNAs that play crucial roles in mRNA translation and decoding. Furthermore, modifications have effect on the lifetimes of nucleic acids in plasma and cells and are consequently incorporated into RNA therapeutics. To provide an analytical tool for sequence characterization of modified RNAs, we developed Pytheas, an open-source software packa ...[more]
