Proteomics

Dataset Information

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Proteomics coupled with in vitro model to study the early crosstalk occurring between newly excysted juveniles of Fasciola hepatica and host intestinal cells


ABSTRACT: Here, we develop a new in vitro model replicating the first interaction of FhNEJ with mouse primary small intestinal epithelial cells (MPSIEC). FhNEJ and MPSIEC were incubated for 3 hours and protein extracts (tegument and soma for FhNEJ and membrane and cytosol for MPSIEC) were subjected to quantitative SWATH-MS proteomics compared with respective controls to evaluate the changes in both the parasite and the host.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Fasciola Hepatica (liver Fluke)

SUBMITTER: David Becerro Recio  

LAB HEAD: Mar Siles-Lucas

PROVIDER: PXD033952 | Pride | 2022-09-20

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
DB_190523-EpiC1-1_Cit.wiff Wiff
DB_190523-EpiC1-1_Cit.wiff.scan Wiff
DB_190523-EpiC1-2_Cit.wiff Wiff
DB_190523-EpiC1-2_Cit.wiff.scan Wiff
DB_190523-EpiC2-1_Cit.wiff Wiff
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