Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Blood Serum
SUBMITTER: Liming Wang
LAB HEAD: Chunying Chen
PROVIDER: PXD033976 | Pride | 2022-10-13
REPOSITORIES: Pride
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Nature communications 20220914 1
How soft corona, the protein corona's outer layer, contributes to biological identity of nanomaterials is largely because capturing protein composition of the soft corona in situ remains challenging. We herein develop an in situ Fishing method that can monitor the dynamic formation of protein corona on ultra-small chiral Cu<sub>2</sub>S nanoparticles (NPs) allowing us to directly separate and identify the corona protein composition. Our method detects spatiotemporal processes in the evolution of ...[more]