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Proteomic analysis of MRSA252 secretome and membrane vesicles

ABSTRACT: The secretome of the Staphylococcus aureus includes specific pathway-exported proteins, as well as cytoplasmic proteins with unknown mechanisms of secretion. As one component of the S. aureus secretome, extracellular membrane vesicles (MVs) are also comprised of secreted and cytoplasmic proteins. However, the contribution of MVs to the secretome of S. aureus has not been investigated. To address this, we performed a proteomic analysis of MVs purified from S. aureus strain MRSA252 along with a similar analysis of the culture supernatans before (S+MV) and after (S-MV) depletion of MVs.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Staphylococcus Aureus

TISSUE(S): Cell Culture

SUBMITTER: Divakara SSM Uppu

LAB HEAD: Jean Claire Lee

PROVIDER: PXD035662 | Pride | 2023-01-26

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	91783- S+MV_1_1.raw	Raw
	91783_SMV_1_1A.pep.xml	Pepxml
	91783_SMV_1_1B.pep.xml	Pepxml
	91784- S+MV_1_2.raw	Raw
	91784_SMV_1_2A.pep.xml	Pepxml

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