Dataset Information

Systemic LRG1 expression in melanoma is associated with disease progression and recurrence

ABSTRACT: Treatment of late-stage melanoma patients with immune checkpoint blockade (ICB) is currently one of the most effective standard therapies. The response rates upon neoadjuvant ICB in stage III melanoma are higher as compared to stage IV disease. Given that successful ICB depends on systemic immune response, we hypothesized that systemic immune suppression might be a mechanism responsible for lower response rates in late-stage disease, and also potentially with disease recurrence in early-stage disease.

INSTRUMENT(S): Q Exactive HF-X, Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

DISEASE(S): Melanoma

SUBMITTER: Peter Robert Mosen

LAB HEAD: Christian Blank

PROVIDER: PXD040399 | Pride | 2024-01-09

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	20180609_OR16_Pr1200_Vollm004_SA_50cm10587814_BMS_PT58stage3_Top12depl_tr1_1_5Ug_DIA.raw	Raw
	20180609_OR16_Pr1200_Vollm004_SA_50cm10587814_BMS_PT58stage4_Top12depl_tr1_1_5Ug_DIA.raw	Raw
	20180610_OR16_Pr1200_Vollm004_SA_50cm10587814_BMS_PT33stage3_Top12depl_tr1_1_5Ug_DIAreal.raw	Raw
	20180610_OR16_Pr1200_Vollm004_SA_50cm10587814_BMS_PT33stage4_Top12depl_tr1_1_5Ug_DIAreal.raw	Raw
	20180610_OR16_Pr1200_Vollm004_SA_50cm10587814_BMS_PT47stage3_Top12depl_tr1_1_5Ug_DIA_real.raw	Raw

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Publications

Rural hospitals' viability and strategic responses.

Ludke R L RL Westhoff L J LJ Flood B M BM

Health progress (Saint Louis, Mo.) 19920501 4

In 1989 the Catholic Health Association, in conjunction with the University of Iowa Center for Health Services Research, surveyed chief executive officers (CEOs) of rural hospitals regarding their hospital's viability and strategic behaviors and orientations. An extensive questionnaire was sent to the CEOs of all Catholic, all other religious not-for-profit, and all investor-owned rural hospitals, as well as to a 50 percent random sample of government and other not-for-profit rural hospitals. CE ...[more]

PMID: 10117404

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