Proteomics

Dataset Information

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Proteome data of a BP1092 mutant of Bordetella pertussis


ABSTRACT: Proteome data of a BP1092 mutant of Bordetella pertussis under virulence modulating and non-modulating conditions

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Bordetella Pertussis (strain Tohama I / Atcc Baa-589 / Nctc 13251)

TISSUE(S): Cell Culture

SUBMITTER: Kristin Surmann  

LAB HEAD: Uwe Völker

PROVIDER: PXD041940 | Pride | 2024-05-24

REPOSITORIES: pride

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Publications

Role of the Putative Histidine Kinase BP1092 in <i>Bordetella pertussis</i> Virulence Regulation and Intracellular Survival.

Debandi Martina M   Carrica Mariela M   Hentschker Christian C   Baroli Carlos C   Völker Uwe U   Rodriguez Maria Eugenia ME   Surmann Kristin K   Lamberti Yanina Y  

Journal of proteome research 20240422 5


<i>Bordetella pertussis</i> persists inside host cells, and virulence factors are crucial for intracellular adaptation. The regulation of <i>B. pertussis</i> virulence factor transcription primarily occurs through the modulation of the two-component system (TCS) known as BvgAS. However, additional regulatory systems have emerged as potential contributors to virulence regulation. Here, we investigate the impact of BP1092, a putative TCS histidine kinase that shows increased levels after bacterial  ...[more]

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