Project description:Hirudo nipponia is an important traditional Chinese medicine resource in China, and the secretions of its salivary glands contain a variety of protein bioactive substances, but due to the low concentration and abundance, they have not been more characterized, and the exploration of its salivary glands is of great significance for the study of the medicinal value and secretion mechanism of leeches. Methods: The expression of differential proteins in salivary gland tissues under starvation (D30) and feeding (D0) states was compared by label-free protein quantification and bioinformatics analysis.
2024-07-03 | PXD045479 | Pride
Project description:Blood-feeding strategy of Hirudo nipponia salivary gland
Project description:We analyzed ORC2 ChIP-Seq from hand dissected salivary glands of wandering third instar larvae from OrR or SuUR Drosophila. Goals were to ascertain the difference in binding profile between salivary glands expressing and not expressing the Supressor of UnderReplication protein. One replicate is included for each of OrR (WT) or SuUR salivary glands.
Project description:Salivary glands are composed of several types of cells, and each cell type is predicted to be involved in the carcinogenesis of different types of cancers. In this study, we performed single nucleus RNA-seq on 3 human salivary gland samples to clarify the gene expression profile of each complex cellular component of the salivary glands.
Project description:We analyzed ORC2 ChIP-Seq from hand dissected salivary glands of wandering third instar larvae from OrR or SuUR Drosophila. Goals were to ascertain the difference in binding profile between salivary glands expressing and not expressing the Supressor of UnderReplication protein.
