Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MRNA expression analysis of radiation-induced skin fibrosis of rats

ABSTRACT: mRNA expression analysis of radiation-induced skin fibrosis of rats

PROVIDER: PRJNA480035 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7479945_1.fastq.gz	Fastqsanger.gz
	SRR7479945_2.fastq.gz	Fastqsanger.gz
	SRR7479946_1.fastq.gz	Fastqsanger.gz
	SRR7479946_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

mRNA expression analysis of radiation-induced skin fibrosis of rats

Project description:This study aims to compared mRNA expression between radiation-induced fibrotic skin and adjacent normal tissues of rats by RNA-Seq. Male Sprague-Dawley (SD) rats (4 weeks old) were irradiated with a single 45-Gy dose of irradiation was administered to the treatment area at a rate of 750 cGy/min using a 6-MeV electron beam accelerator (Clinac 2100EX, Varian Medical Systems, Inc., CA). Skin tissues from nonirradated skin areas and irradietd areas were collected and subjected to mRNA expression analysis.

2018-07-13 | GSE116745 | GEO

DNA methylation analysis of radiation-induced skin fibrosis of rats

Project description:DNA methylation analysis of radiation-induced skin fibrosis of rats

| PRJNA480034 | ENA

DNA methylation analysis of radiation-induced skin fibrosis of rats

Project description:This study aims to compared the genome-wide DNA methylation status in radiation-induced fibrotic skin and adjacent normal tissues of rats by methylated DNA immunoprecipitation sequencing (MeDIP-Seq). Male Sprague-Dawley (SD) rats (4 weeks old) were irradiated with a single 45-Gy dose of irradiation was administered to the treatment area at a rate of 750 cGy/min using a 6-MeV electron beam accelerator (Clinac 2100EX, Varian Medical Systems, Inc., CA). Skin tissues from nonirradated skin areas and irradietd areas were collected and subjected to DNA methylation analysis by MeDIP.

2018-07-13 | GSE116747 | GEO

Single-cell analysis reveals the progress in skin repair after radiation in rats.

Project description:This study aims to compare the cell heterogeneity and mRNA expression between irradiated and non-irradiated rat skin tissues at the single cell level. In this study, the skin was isolated from rats with radiation or non-irradiated rats. Male Sprague Dawley (SD) rats (6 weeks of age) were used. For irradiation, the hair on the gluteal region of the rats was shaved using a razor. The animals were immobilized using adhesive tape on a plastic plate to minimize motion during radiation exposure. A 3-cm-thick piece of lead was used to shield the animals and localize the radiation field (3-4 cm). Irradiation was performed on the treatment area at a dose rate of 1000 cGy/min using a 6-MeV electron beam accelerator. Irradiated skin was taken on day 7, 14, 28 and 60 for RNA-seq, respectively. The control group of skin were collected from four rats without radiation and mixed for RNA-seq.

2022-01-19 | GSE193564 | GEO

ChIP-Sequencing analysis of YY1 binding DNA in radiation-induced skin fibrosis of rats

Project description:This study aims to compared the genome-wide Ying Yang-1 (YY1) binding DNA sequences in radiation-induced fibrotic skin and adjacent normal tissues of rats by ChIP-Seq. Male Sprague-Dawley (SD) rats (4 weeks old) were irradiated with a single 45-Gy dose of irradiation was administered to the treatment area at a rate of 750 cGy/min using a 6-MeV electron beam accelerator (Clinac 2100EX, Varian Medical Systems, Inc., CA). Skin tissues from nonirradated skin areas and irradietd areas were collected and subjected to ChIP of YY1.

2018-07-13 | GSE116746 | GEO

ChIP-Sequencing analysis of YY1 binding DNA in radiation-induced skin fibrosis of rats

Project description:ChIP-Sequencing analysis of YY1 binding DNA in radiation-induced skin fibrosis of rats

| PRJNA480036 | ENA

RNA-seq, YY1 ChIP-seq and MeDIP-seq of radiation-induced skin fibrosis of rats

Project description:RNA-seq, YY1 ChIP-seq and MeDIP-seq of radiation-induced skin fibrosis of rats

| PRJNA480033 | ENA

mRNA expression analysis of irradiated skin tissues of mice

Project description:Radioactive materials have been widely used in industry, medicine, science, the military and nuclear facilities, which has significantly increased the potential of large-scale, uncontrolled exposure to radiation. The skin is one of the radiosensitive organ systems and radiation-induced skin injury remains a serious concern after ionizing radiation exposure. This study aims to illustrate the early response (mRNA profiles) of skin tissues following radiation and find targets against radiation-induced skin injury.

2020-04-23 | GSE130183 | GEO

Single-cell analysis reveals the progress in skin repair after radiation in rats.

Project description:Single-cell analysis reveals the progress in skin repair after radiation in rats.

| PRJNA796596 | ENA