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Paradoxical CD4 decline on ART: a novel, rare and perplexing immunologic outcome

ABSTRACT: Paradoxical CD4 decline on ART: a novel, rare and perplexing immunologic outcome

PROVIDER: PRJNA515603 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8450180_1.fastq.gz	Fastqsanger.gz
	SRR8450180_2.fastq.gz	Fastqsanger.gz
	SRR8450190_1.fastq.gz	Fastqsanger.gz
	SRR8450190_2.fastq.gz	Fastqsanger.gz
	SRR8450171_1.fastq.gz	Fastqsanger.gz

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Paradoxical CD4 decline on ART: a novel, rare and perplexing immunologic outcome

Project description:The goal of antiretroviral therapy (ART) is to suppress HIV-1-replication and reconstitute CD4-T-cells. Here, we report on HIV-infected individuals, who had a paradoxical decline in CD4-T-cells despite ART-mediated suppression of plasma HIV-1 load (plHIV-1). We defined such immunological outcome as extreme immune decline (EXID).

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