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RNA-seq for hand-microdissected glomeruli from Immunoglobulin A nephropathy patients

ABSTRACT: RNA-seq for hand-microdissected glomeruli from Immunoglobulin A nephropathy patients

PROVIDER: PRJNA593015 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR10574400_1.fastq.gz	Fastqsanger.gz
	SRR10574400_2.fastq.gz	Fastqsanger.gz
	SRR10574401_1.fastq.gz	Fastqsanger.gz
	SRR10574401_2.fastq.gz	Fastqsanger.gz
	SRR10574402_1.fastq.gz	Fastqsanger.gz

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RNA-seq for hand-microdissected glomeruli from Immunoglobulin A nephropathy patients

Project description:We collected glomeruli from biopsy specimens from IgA nephropathy patients with relatively preserved kidney function (eGFR ≥ 60 mL/min/1.73 m2 and urine protein-to-creatinine ratio < 3 g/g) and from normal kidney cortices by hand microdissection and performed RNA-seq. The transcriptomic profiling of IgA nephropathy glomerulus provide insights for intraglomerular pathophysiology of IgAN before reaching profound kidney dysfunction.

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