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ABSTRACT: Eucommia Ulmoides Leaves Extract Alleviates Inflammation bowel disease through Modulating the Gut Microbiota-Bile acids-TGR5 Axis

PROVIDER: PRJNA730339 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR14569500.fastq.gz	Fastqsanger.gz
	SRR14569501.fastq.gz	Fastqsanger.gz
	SRR14569502.fastq.gz	Fastqsanger.gz
	SRR14569503.fastq.gz	Fastqsanger.gz
	SRR14569504.fastq.gz	Fastqsanger.gz

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Gene expression data from liver of rat fed a high-fat diet and high-fructose water without/with Eucommia ulmoides leaves

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Gene expression data from liver of rat fed a high-fat diet and high-fructose water without/with Eucommia ulmoides leaves

Project description:To investigate effects of intake of Eucommia ulmoides leaves on hyperlipidemia, we performed gene expression profiling on rat liver by microarray analysis. Microarray analysis revealed that Eucommia ulmoides leaves up-regulated the gene expression involved in alpha-, beta-, and omega-oxidation of fatty acids, mainly relating to peroxisome proliferator-activated receptor signaling pathway. Rats were fed a high-fat diet and high-fructose water without/with orally administration of Eucommia ulmoides leaves for 5 weeks. Livers were taken for RNA extraction and hybridization on Agilent microarrays.

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