Project description:CT45 family members are increased in several tumor types. However, molecules of action of CT45A1 in colorectal cancer (CRC) are elusive. In an attempt to understand the biological and clincal significance of CT45A1 in CRC, we generated the CT45A1-expressing CRC lines for identifying CT45A1-regulatory circuit.
Project description:Ovarian cancer (OC) is the leading cause of death from gynecologic malignancies. The most difficult issue in the treatment of ovarian cancer is the eventual development of platinum resistance. Accumulating studies have shown that circRNAs are abnormally aberrantly expressed in tumors and play critical roles in tumor growth, metastasis, stemness and resistance to therapy.To identify circRNAs that play crucial roles in maintaining the platinum resistance of ovarian cacner, we performed RNA-seq analysis in platinum-resistant(n=9) and -sensitive(n=10) ovarian cacner tissues. Candidate genes were identified by bioinformatic analysis and literature review.
Project description:RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
Project description:RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
Project description:RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
Project description:Colorectal cancer were diagnosed by colonoscopy and pathology and collected at after surgery.The colorectal cacner proteomes were analyzed for 6 normal mucosal tissues and 6 colorectal cancer mucosal tissues by liquid-chromatography mass spectrometry
Project description:In this study,comparative genomic, transcriptomic and secretomic profilings of Penicillium oxalicum HP7-1 and its cellulase and xylanase hyper-producing mutant EU2106 were employed to screen for novel regulators for cellulase and xylanase gene expression.
Project description:RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D
Project description:RAW files of corresponding Baits used in Extensive Rewiring of the EGFR Network in Colorectal Cancer Cells Expressing Transforming Levels of KRASG13D