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3D chromatin architecture of drug-tolerant cancer cells at single-cell resolution (Reference dataset of population cells)

ABSTRACT: 3D chromatin architecture of drug-tolerant cancer cells at single-cell resolution (Reference dataset of population cells)

PROVIDER: PRJNA802208 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR17836751_1.fastq.gz	Fastqsanger.gz
	SRR17836751_2.fastq.gz	Fastqsanger.gz
	SRR17836752_1.fastq.gz	Fastqsanger.gz
	SRR17836752_2.fastq.gz	Fastqsanger.gz
	SRR17836753_1.fastq.gz	Fastqsanger.gz

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3D chromatin architecture of drug-tolerant cancer cells at single-cell resolution (Reference dataset of population cells)

Project description:Anticancer drug therapy generally elicits the drug tolerance after long-term treatment. Recent studies suggested that 3D chromatin structures of cancer cells were intimately linked to drug resistance. However, 3D chromatin structures in drug-tolerant cancer cells at single-cell resolution haven’t been elucidated. Here we performed single-cell Hi-C (scHi-C) analysis to examine the 3D chromatin structures in three stages of breast cancer cells. Population cells Hi-C data as the reference.

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