Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

CD45+ and CD45- cells of benign v/s metastatic mouse breast tumors

ABSTRACT: CD45+ and CD45- cells of benign v/s metastatic mouse breast tumors

PROVIDER: PRJNA869583 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

CD45+ and CD45- cells of benign v/s metastatic mouse breast tumors

Project description:Metastasis remains a leading cause of all cancer related mortalities and therapeutic challenges. To successfully establish tumors and metastasiz, cancer cells must escape recognition and elimination by modulating immune cells during surveillance. Therapies that mount anti-tumor response of the adaptive immune system and target the immune evasion mechanisms have entered the clinic. However, the number of patients that respond to these therapies remains humble. This is likely due to the pro-tumor and immunosuppressive mechanisms of innate immune system that remain elusive. Tumor immune cells demonstrate tremendous intra- and inter-tumoral heterogeneity. Presence of high neutrophil to lymphocyte ratio is typically associated with high risk of metastasis and poor patient outcome, which suggests that immune cells, specifically myeloid cells of metastatic tumors have distinct biological functions. We aim to identify these distinct biological functions and the candidates that may have prognostic and therapeutic potential using a non-metastatic and metastatic tumor from the 4T1 mouse breast cancer model.

2023-11-22 | GSE211223 | GEO

Circulating microRNA Biomarker for Detecting Breast Cancer in High-Risk Benign Breast Tumors

Project description:We sought to identify circulating microRNAs (miRNAs) from blood plasma that could be used as biomarkers to detect breast cancer existing in high-risk benign breast tumors. Plasma samples were collected from patients with early-stage breast cancer (CA), high- (HB), moderate- (MB), and no-risk (Be) benign tumors. The miRNAs we have identified have the potential to develop into a crucial blood-based screening tool to help monitor the development of breast cancer in benign breast tumors.

2023-04-20 | GSE225117 | GEO

Proteomics profiling in primary tumors of metastatic and non-metastatic breast cancers

Project description:Analysis of different proteomics profile in primary tumors of metastatic and non-metastatic breast cancers.

2023-03-09 | PXD037288 | Pride

miRNA in benign tumors

Project description:miRNA expression profiles from benign breast tumors, breast cancers, and normal breast tissue

2011-03-01 | E-MTAB-471 | biostudies-arrayexpress

CD45+ vs CD45- RCC proteome characterization

Project description:Exploration of proteome differences between CD45+ and CD45- cell types in renal cell carcinoma tumors and normal adjacent tissue patient samples.

2020-10-14 | PXD014370 | Pride

Circulating microRNA Biomarker for Detecting Breast Cancer in High-Risk Benign Breast Tumors

Project description:Circulating microRNA Biomarker for Detecting Breast Cancer in High-Risk Benign Breast Tumors

| PRJNA934049 | ENA

Human benign adrenocortical tumors miRNome

Project description:Human benign adrenocortical tumors miRNome

| PRJEB25822 | ENA

lncRNAs differentially expressed in benign and malignant phyllodes tumors [array]

Project description:To investigate the pathogenesis of malignant phyllodes tumors of the breast, we used lncRNA+mRNA microarray expression profiling as a platform to investigate lncRNAs that play a key role in the malignant progression of phyllodes tumors of the breast.A total of 4 cases of breast fibroadenomas, 6 cases of benign phyllodes tumors and 6 cases of malignant phyllodes tumors were included. Fibroadenomas and benign phyllodes tumors were used as controls to screen out significantly differentially expressed lncrnas in malignant phyllodes tumors.

2024-06-20 | GSE235267 | GEO

Transcription profiling by array of human benign prostate, primary and metastatic prostate cancer samples to reveal signatures of metastatic progression

Project description:An integrative analysis of this compendium of proteomic alterations and transcriptomic data was performed revealing only 48-64% concordance between protein and transcript levels. Importantly, differential proteomic alterations between metastatic and clinically localized prostate cancer that mapped concordantly to gene transcripts served as predictors of clinical outcome in prostate cancer as well as other solid tumors. Keywords: prostate cancer progression 13 individual benign prostate, primary and metastatic prostate cancer samples and 6 pooled samples from benign,primary or metastatic prostate cancer tissues.

2005-09-20 | E-GEOD-3325 | biostudies-arrayexpress

Quantitative Proteomics by SWATH-MS reveals molecular differences among malignant and benign breast tumors in Mexican woman

Project description:Breast tumors are produced by an uncontrollable cell proliferation mechanism and can be classified as benign (TMB) or malignant (TMM). TMM or breast cancer is the neoplasia with the highest incidence and mortality in Mexican women. Over time, some types of TMB can transform into a TMM. However, the mechanisms involved in such processes remain elusive and limited studies have examined the molecular differences between TMB and TMM. Hence, the aim of this study was to evaluate and compare the proteomic profile of TMB (n = 10) and TMM (n = 6) of Mexican women.

2024-10-22 | PXD019334 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data