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GenomicsGenome-wide association study of response to warfarin in a UK prospective cohort
Genome-wide association study of Warfarin dosing in 714 British, recruited in Liverpool and Birmingham. Three phenotypes were investigated: warfarin mean dose, warfarin mean stable dose, and INR over 4 during first week of treatment. Stability was defined by at least three INR measurements within tar...
EGAS00001001130 | EGA
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GenomicsUK Warfarin Consortium
Data Access Committee EGAC00001000301
EGAC00001000301 | EGA
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Genomics610K_imputed - samples
610k genotyping imputed on Hapmap 3 and 1000G Phase 1 CEU
EGAD00010000704 | EGA
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Genomics,MultiomicsSpatiotemporal Transcriptome of the Human Brain

Comprehensive knowledge about the spatiotemporal dynamics of the brain transcriptome is essential for a better understanding of neurodevelopment, sexual dimorphism, and evolution, as well as our increased susceptibility to certain brain disorders. We generated and analyzed genome-wide exon...

phs000406.v1.p1 | EGA
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TranscriptomicsTranscription profiling of mouse diaphragm, comparison of wild type and mdx mice, 7 to 112 days
Determination of gene expression changes in diaphragm muscle of mdx (dystrophin-deficient) mice at postnatal ages 7, 14, 23, 28, 56, and 112 days. 3 independent replicates/age/strain. Data form part of publication: Human Molecular Genetics 13:257-269, 2004.
ORGANISM(S): Mus musculus 
2007-10-05 | E-GEOD-1026 | biostudies-arrayexpress
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TranscriptomicsTranscription profiling of rat extraocular and gastrocnemius/soleus muscles during postnatal development
Conserved and muscle group-specific gene expression patterns shape postnatal development of the novel extraocular muscle phenotype. Comparison of postnatal development of extraocular and hindlimb muscle between birth and P45.
ORGANISM(S): Rattus norvegicus 
2007-10-12 | E-GEOD-903 | biostudies-arrayexpress
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TranscriptomicsSpatio-temporal transcriptome of the human brain
The development of the human brain is a complex and precisely regulated process that unfolds over a protracted period of time. Human-specific features of this process, especially the ways in which highly complex neural circuits of the cerebral cortex form, are likely to be important factors in the ev...
ORGANISM(S): Homo sapiens 
2011-10-26 | E-GEOD-25219 | biostudies-arrayexpress
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Genomics,MultiomicsFramingham Cohort

Startup of Framingham Heart Study. Cardiovascular disease (CVD) is the leading cause of death and serious illness in the United States. In 1948, the Framingham Heart Study (FHS) -- under the direction of the National Heart Institute (now known as the National Heart, Lung, and Blood Institut...

phs000007.v17.p6 | EGA
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Genomics,MultiomicsDiscovery of Non-ETS Gene Fusions in Human Prostate Cancer using Next Generation RNA Sequencing

Half of prostate cancers harbor gene fusions between TMPRSS2 and members of the ETS transcription factor family. To date little is known about the presence of non-ETS fusion events in prostate cancer. We employed next-generation transcriptome sequencing (RNA-Seq) in order to ex...

phs000310.v1.p1 | EGA
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GenomicsNHLBI Jackson Heart Study Candidate Gene Association Resource (CARe)

The Jackson Heart Study (JHS) is a large, community-based, observational study whose participants were recruited from urban and rural areas of the three counties (Hinds, Madison and Rankin) that make up the Jackson, Mississippi, metropolitan statistical area (MSA). Participants were enrolled fr...

phs000286.v2.p1 | EGA
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