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ProteomicsSemen of gibel carp - Distinct sperm nucleus behaviors between genotypic and temperature-dependent sex determination males are associated with replication and expression-related pathways in a gynogenetic fish
In our study, differential male nucleus events and development behaviors were revealed from the fertilized eggs in response to the sperm from males of genotypic sex determination (GSD) and temperature-dependent sex determination (TSD) in gibel carp. When the eggs of maternal fish were fertilized by th...
ORGANISM(S): Carassius Gibelio 
2018-06-14 | PXD008919 | Pride
Gibel carp Tsd Semen proteomics Gsd Itraq 
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ProteomicsEngineered Pichia pastoris LC-MSMS
Samples of PCH, LH73H and LH119H were cultivated according to the culture method of shake flask cultivation and then collected for protein extraction.
ORGANISM(S): Fungi Komagataella Pastoris (strain Gs115 / Atcc 20864) (yeast) (pichia Pastoris) 
2024-08-10 | PXD048269 | Pride
Lc-msms Pichia pastoris 
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ProteomicsMouse Skin LC-MS/MS
Previously, we reported that a null mutation of the Zdhhc13 gene caused by ethylnitrosourea (ENU) mutagenesis in mice resulted in severe systematic phenotypes with amyloidosis, alopecia, dermatitis and osteoporosis. In this study we continued to delineate the pathological mechanism for the dermatitis ...
ORGANISM(S): Mus Musculus (mouse) 
2022-02-25 | PXD002958 | Pride
Mouse skin tissue Palmitoylation Lc-ms/ms 
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ProteomicsReciprocal regulation of the TOR kinase and ABA receptor balances plant growth and stress response
...onses through phosphorylation at a conserved serine residue of Abscisic acid receptor PYR1/PYLs/RCARs. The phosphorylation inhibits the function of PYLs and prevents the binding of PYLs to abscisic acid and its downstream substrates of PP2C, which blocks the ABA and stress signaling. Our results sugge...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2017-12-01 | PXD003746 | Pride
Phosphorylation Aba receptor Abscisic acid Snrk2 Raptor Target of rapamycin 
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UnknownMorphology, molecular genetics, and acoustics reveal two new species of the genus Leptobrachella from northwestern Guizhou Province, China (Anura, Megophryidae).
Not available
S-EPMC6536485 | biostudies-literature
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ProteomicsYBX1-IP in mouse bone marrw myeloma cells
The total protein of bone marrw myeloma cells was extracted with cell lysis buffer for IP. YBX1 antibody was used to perform Immunoprecipitation.
ORGANISM(S): Mus Musculus (mouse) 
2023-04-19 | PXD039386 | Pride
Ybx1-ip Bmscs 
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MetabolomicsFatty acid oxidation protects cancer cells from apoptosis through increasing mitochondrial membrane lipids

Overcoming resistance to chemotherapies remains a major unmet need for cancers such as triple negative breast cancer (TNBC). Therefore, mechanistic studies to provide insight for drug development are urgently needed to overcome TNBC therapy resistance. Recently, an important role of fatty acid...
...STAT3 upregulates expression of long-chain acyl-CoA synthetase 4 (ACSL4), resulting in increased phospholipid synthesis. Elevating phospholipids in mitochondrial membranes leads to heightened mitochondrial integrity, which in turn overcomes chemotherapy-induced tumor cell apoptosis. Conversely, in both cultured tumor cells and xenograft tu...

2022-05-31 | MTBLS4709 | MetaboLights
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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae to...
2022-03-04 | MTBLS4132 | MetaboLights
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ProteomicsMouse Liver S-Palmitoylation ZDHHC13 LC-MS/MS
Protein S-palmitoylation is a reversible post-translational modification which adding 16-carbon palmitate to specific cysteines and contributes to variable biological functions such as protein trafficking, scaffolding and signaling. ZDHHC13 is one of the members of DHHC-containing palmitoyl-acyltransf...
ORGANISM(S): Mus Musculus (mouse) 
2017-09-29 | PXD003039 | Pride
S-palmitoylation Zdhhc13 Mouse Liver Lc-ms/ms 
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UnknownA novel laser-collider used to produce monoenergetic 13.3 MeV (7)Li (d, n) neutrons.
Not available
S-EPMC4889997 | biostudies-other
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