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ProteomicsiTRAQ-based proteomic analysis reveals genome-wide protein expression patterns in allohexaploid bread wheat in adaptation to potassium deficiency and an important role of jasmonic acid
Two-week old bread wheat seedlings hydroponically grown Hoagland solution were transferred to potassium (K+)-free conditions for 8 d, their root and leaf proteome profiles were assessed using iTRAQ proteome method, and NCBInr database combined with the recently published bread wheat genome informatio...
ORGANISM(S): Triticum Aestivum (wheat) 
2017-10-09 | PXD003570 | Pride
Triticum aestivum l. Potassium deficiency Itraq Jasmonic acid 
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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae t...
2022-03-04 | MTBLS4132 | MetaboLights
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ProteomicsComprehensive profiling of lysine ubiquitome reveals diverse functions of lysine ubiquitination in common wheat
Protein ubiquitination, which is a major post-translational modifications that occurs in eukaryotic cells, is involved in diverse biological processes. To date, large-scale profiling of the ubiquitome in common wheat has not been reported, despite its status as the major cereal crop in the world. Her...
ORGANISM(S): Triticum Aestivum (wheat) 
2017-11-01 | PXD007243 | Pride
proteomics Triticum aestivum l.  post-translational modification  lysine ubiquitination  proteomics  mass spectrometry lysine ubiquitination mass spectrometry post-translational modification Triticum aestivum l. 
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TranscriptomicsTranscription profiling by array of Nipponbare rice roots over a time course of potassium deprivation
Potassium (K+) is one of the most important nutrient ions in plant cells and play crucial roles in many plant physiological and developmental processes. K+ deficiency is the common abiotic stress in natural environment, which inhibits plant growth and reduces production of crops. We used microarrays ...
ORGANISM(S): Oryza sativa japonica 
2012-10-31 | E-GEOD-37161 | biostudies-arrayexpress
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ProteomicsHuman lymphoma cell membrane proteomics by Pitchfork strategy
We combined glycopeptide enrichment by SPEG (Tian et al., 2007) with a hydrophobic segment-oriented hpTC method (Vít et al 2016) and a standard “detergent and trypsin” approach into a tree-pronged “Pitchfork” strategy for the analysis of membrane proteome in human lymphoma cells.
ORGANISM(S): Homo Sapiens (human) 
2019-03-29 | PXD012647 | Pride
Hptc Speg Lymphoma Imp Membrane proteins 
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ProteomicsLC-MS/MS analysis of immunoprecipitation samples of Tetrahymena Mediator complex associated proteins
...f the genome is transcribed into noncoding RNA (ncRNA). This ncRNA serves to spot transposable elements (TEs) and other unwanted DNA sequences and marks them for elimination from the soma of the progeny. ncRNA transcription is remarkable for its extent, its occurrence in a nucleus that bears heteroch...
ORGANISM(S): Tetrahymena Thermophila Sb210 
2019-07-11 | PXD012372 | Pride
Emit2 Rib1 Emit1 Tetrahymena thermophila Mediator complex 
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ProteomicsAXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
...ious critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we identify AXIN acts as an effective regulator of antiviral innate immunity against both DNA and RNA virus infections. In the resting s...
ORGANISM(S): Homo Sapiens (human) 
2024-10-31 | PXD055972 | Pride
Human Irf3 Axin1 
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ProteomicsAXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
...ious critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune response remains largely unknown. Here, we identify AXIN acts as an effective regulator of antiviral innate immunity against both DNA and RNA virus infections. In the resting s...
ORGANISM(S): Homo Sapiens (human) 
2024-11-01 | PXD055574 | Pride
Human Irf3 Axin1 
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ProteomicsSuccinylome analysis reveals the involvement of lysine succinylation in extreme resistance of Deinococcus radiodurans
Increasing evidences showing that succinylation of lysine residue mainly regulates enzymes involved in the carbon metabolism pathway, both in prokaryotic and eukaryotic cells. Deinococcus radiodurans is one of the most radioresistant organisms on earth, which is famous for its robust resistance. A ma...
ORGANISM(S): Deinococcus Radiodurans 
2021-04-26 | PXD012149 | Pride
posttranslational modification nucleic acid binding succinylation dna repair Succinylome Succinylome  succinylation  dna repair  nucleic acid binding  posttranslational modification 
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ProteomicsMining for protein S-sulfenylation in Arabidopsis uncovers redox-sensitive sites
...eroxide (H2O2) is an important messenger molecule for diverse cellular processes. H2O2 oxidizes proteinaceous cysteinyl thiols to sulfenic acid, also known as S-sulfenylation, thereby affecting the protein conformation and functionality. Although many proteins have been identified as S-sulfenylation ...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2019-09-16 | PXD013495 | Pride
Chemoproteomics Btd Sulfenic acid 
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