Functional characterisation of CpG islands in mouse tissues
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ABSTRACT: Tissue-specific methylation patterns suggest a role for CpG island (CGI) methylation in differentiation and cell-type-specific gene regulation. We have applied CXXC affinity purification (CAP), MBD affinity purification (MAP) and chromatin immunoprecipitation (ChIP) in combination with solexa sequencing to investigate the extent and functional significance of CGI methylation in mouse sperm, blood, cerebellum and ES cells.
INSTRUMENT(S): Illumina HiSeq 2000
ORGANISM(S): mus musculus
DISEASE(S): not yet visible
SUBMITTER:
PROVIDER: E-ERAD-53 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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