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Variations in stress sensitivity and genomic expression in diverse S. cerevisiae strains (CGH)

ABSTRACT: Gene expression variation was measured in 17 non-laboratory strains compared to the sequenced S288c lab strain Keywords: comparative genomic hybridizations (CGH) comparing different yeast strains Each strain was grown in at least biological triplicate to log phase in rich (YPD) medium. Extracted total RNA was compared to that collected from the diploid S288C strain, DBY8268 (ura3-52/ura3-delta, ho/ho, GAL2/GAL2)

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Daniel Kvitek

PROVIDER: E-GEOD-10267 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Variations in stress sensitivity and genomic expression in diverse S. cerevisiae isolates.

Kvitek Daniel J DJ Will Jessica L JL Gasch Audrey P AP

PLoS genetics 20081017 10

Interactions between an organism and its environment can significantly influence phenotypic evolution. A first step toward understanding this process is to characterize phenotypic diversity within and between populations. We explored the phenotypic variation in stress sensitivity and genomic expression in a large panel of Saccharomyces strains collected from diverse environments. We measured the sensitivity of 52 strains to 14 environmental conditions, compared genomic expression in 18 strains, ...[more]

PMID: 18927628

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