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Unknown,Transcriptomics,Genomics,Proteomics

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Glomerular Transcriptome from European Renal cDNA Bank subjects and living donors

ABSTRACT: Glomerular Transcriptome from European Renal cDNA Bank subjects and living donors. Samples included in this analysis have been previously analyzed using older CDF definitions and are included under previous GEO submissions - GSE47183 (chronic kidney disease samples), and GSE32591 (IgA nephropathy samples). RNA from the glomerular compartment of was extracted and processed for hybridization on Affymetrix microarrays, annotated using Human Entrez Gene ID custom CDF version 19. This dataset is part of the TransQST collection.

ORGANISM(S): Homo sapiens

SUBMITTER: Sean Eddy

PROVIDER: E-GEOD-104948 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Metabolic pathways and immunometabolism in rare kidney diseases.

Grayson Peter C PC Eddy Sean S Taroni Jaclyn N JN Lightfoot Yaíma L YL Mariani Laura L Parikh Hemang H Lindenmeyer Maja T MT Ju Wenjun W Greene Casey S CS Godfrey Brad B Cohen Clemens D CD Krischer Jeffrey J Kretzler Matthias M Merkel Peter A PA

Annals of the rheumatic diseases 20180503 8

<h4>Objectives</h4>To characterise renal tissue metabolic pathway gene expression in different forms of glomerulonephritis.<h4>Methods</h4>Patients with nephrotic syndrome (NS), antineutrophil cytoplasmic antibody-associated vasculitis (AAV), systemic lupus erythematosus (SLE) and healthy living donors (LD) were studied. Clinically indicated renal biopsies were obtained at time of diagnosis and microdissected into glomerular and tubulointerstitial compartments. Microarray-derived differential ge ...[more]

PMID: 29724730

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