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AURATUS goldfish environmental genomics projects: lumiestrone in the liver

ABSTRACT: Sexually inactive male goldfish were injected i.p. with lumiestrone (0.5 µg/g) or control vehicle (in charcoal-stripped peanut oil; 5 µL/g) to investigate the biological activity of lumiestrone. A common reference design was used: 4 independent groups of sexually inactive male goldfish treated with 0.5 ug/g lumiestrone hybridized against a common vehicle control. Slides 2, 15, 20, 43.

ORGANISM(S): Carassius auratus

SUBMITTER: Jason Popesku

PROVIDER: E-GEOD-12252 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Lumiestrone is Photochemically Derived from Estrone and may be Released to the Environment without Detection.

Trudeau Vance L VL Heyne Belinda B Blais Jules M JM Temussi Fabio F Atkinson Susanna K SK Pakdel Farzad F Popesku Jason T JT Marlatt Vicki L VL Scaiano Juan C JC Previtera Lucio L Lean David R S DR

Frontiers in endocrinology 20111202

Endocrine disrupting chemicals are adversely affecting the reproductive health and metabolic status of aquatic vertebrates. Estrone is often the dominant natural estrogen in urban sewage, yet little is known about its environmental fate and biological effects. Increased use of UV-B radiation for effluent treatments, and exposure of effluents to sunlight in holding ponds led us to examine the effects of environmentally relevant levels of UV-B radiation on the photodegradation potential of estrone ...[more]

PMID: 22654829

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AURATUS goldfish environmental genomics projects: quinpirole in the telencephalon

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2013-03-20 | E-GEOD-14609 | biostudies-arrayexpress

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2011-08-21 | E-GEOD-14607 | biostudies-arrayexpress

AURATUS goldfish environmental genomics projects: SKF 38393 in the telencephalon

Project description:Sexually mature female goldfish were administered 2 i.p. injections: 1) 0.1% DMSO in 0.6% saline or SKF 38393 (40 µg/g) dissolved in 0.1% DMSO in 0.6% saline, and; 2) 0.6% saline. A common reference design was used: 4 independent groups of telencephali from sexually mature female goldfish treated with 40 ug/g SKF 38393 hybridized against a common vehicle control. Slides 7, 13, 30, 47.

2013-03-20 | E-GEOD-14608 | biostudies-arrayexpress

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2013-03-20 | E-GEOD-16044 | biostudies-arrayexpress

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