Unknown,Transcriptomics,Genomics,Proteomics

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AURATUS goldfish environmental genomics projects: dopamine antagonists


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Carassius auratus

SUBMITTER: Jason Popesku 

PROVIDER: E-GEOD-15763 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Meta-type analysis of dopaminergic effects on gene expression in the neuroendocrine brain of female goldfish.

Popesku Jason T JT   Martyniuk Christopher J CJ   Trudeau Vance L VL  

Frontiers in endocrinology 20121102


Dopamine (DA) is a major neurotransmitter important for neuroendocrine control and recent studies have described genomic signaling pathways activated and inhibited by DA agonists and antagonists in the goldfish brain. Here we perform a meta-type analysis using microarray datasets from experiments conducted with female goldfish to characterize the gene expression responses that underlie dopaminergic signaling. Sexually mature, pre-spawning [gonadosomatic index (GSI) = 4.5 ± 1.3%] or sexually regr  ...[more]

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