Effect of U94 in Gene Expression in PC3 Cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Warren Johnson
PROVIDER: E-GEOD-1868 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
U94 alters FN1 and ANGPTL4 gene expression and inhibits tumorigenesis of prostate cancer cell line PC3.
Ifon Ekwere T ET Pang Alan L Y AL Johnson Warren W Cashman Kathleen K Zimmerman Sharon S Muralidhar Sumitra S Chan Wai-Yee WY Casey John J Rosenthal Leonard Jason LJ
Cancer cell international 20050622
<h4>Background</h4>Insensitivity of advanced-stage prostate cancer to androgen ablation therapy is a serious problem in clinical practice because it is associated with aggressive progression and poor prognosis. Targeted therapeutic drug discovery efforts are thwarted by lack of adequate knowledge of gene(s) associated with prostate tumorigenesis. Therefore there is the need for studies to provide leads to targeted intervention measures. Here we propose that stable expression of U94, a tumor supp ...[more]
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