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S. aureus gene expression during growth phase and/or S. aureusâ??PMN interaction

ABSTRACT: To measure S. aureus gene expression during growth phase and/or S. aureusâ??PMN interaction.

ORGANISM(S): Staphylococcus aureus

SUBMITTER: Stephen Porcella

PROVIDER: E-GEOD-2728 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Insights into mechanisms used by Staphylococcus aureus to avoid destruction by human neutrophils.

Voyich Jovanka M JM Braughton Kevin R KR Sturdevant Daniel E DE Whitney Adeline R AR Saïd-Salim Battouli B Porcella Stephen F SF Long R Daniel RD Dorward David W DW Gardner Donald J DJ Kreiswirth Barry N BN Musser James M JM DeLeo Frank R FR

Journal of immunology (Baltimore, Md. : 1950) 20050901 6

Polymorphonuclear leukocytes (PMNs, or neutrophils) are critical for human innate immunity and kill most invading bacteria. However, pathogens such as Staphylococcus aureus avoid destruction by PMNs to survive, thereby causing human infections. The molecular mechanisms used by pathogens to circumvent killing by the immune system remain largely undefined. To that end, we studied S. aureus pathogenesis and bacteria-PMN interactions using strains originally isolated from individuals with community- ...[more]

PMID: 16148137

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S. aureus gene expression during growth phase and/or S. aureus–PMN interaction

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