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Genome wide DNA methylation analysis of leukemia and reprogrammed leukemia cells (sequencing)

ABSTRACT: We analyzed the methylation pattern of a well characterized leukemia cell line, named K562. Furthermore, we decided to investigate how the malignant epiegenome change during the reprogramming process We used RRBS analysis to investigate the methylation pattern in leukemia and reprogrammed leukemia (LiPS).We show that the erasure of the epigenetic aberrancies have functional consequences on leukemia phenotype

ORGANISM(S): Homo sapiens

SUBMITTER: Touati Benoukraf

PROVIDER: E-GEOD-33230 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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