Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

An Organ Culture System to Model Early Degenerative Changes of the Intervertebral Disc: II Profiling Global Gene Expression Changes


ABSTRACT: To mimic a degenerative insult, rat intervertebral discs were cultured in the presence of TNF-alpha, IL-1beta and serum limiting conditions. Gene expression analysis was performed using a microarray to identify differential gene expression between experimental and control groups. The discs were collected and the annulus fibrosus (AF) was separated from the nucleus pulposus (NP). Total RNA from NP was used for RNA extraction and hybridization on Affymetrix microarrays: Control group - Ctr-1, Ctr-2, Ctr-3, Ctr-4 and Experimental group-Exp-1, Exp-2, Exp-3, Exp-4.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Dessislava Markova 

PROVIDER: E-GEOD-42611 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2022-06-09 | PXD018968 | Pride
2014-05-27 | E-GEOD-55844 | biostudies-arrayexpress
2008-06-14 | E-GEOD-6300 | biostudies-arrayexpress
2021-10-18 | E-MTAB-7451 | biostudies-arrayexpress
2016-07-14 | E-MTAB-4635 | biostudies-arrayexpress
2015-02-13 | E-GEOD-59078 | biostudies-arrayexpress
2013-11-25 | E-GEOD-39389 | biostudies-arrayexpress
2022-03-31 | GSE199866 | GEO
2012-10-03 | E-GEOD-26678 | biostudies-arrayexpress
2020-12-03 | PXD019151 | Pride