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Profiling of Dolphin Skin Cells

ABSTRACT: 3 technical replicates from Wild Dolphin PBL Keywords: Immune and stress response analysis Analyzed 3 arrays with a 3 replicate series.

ORGANISM(S): Tursiops truncatus

SUBMITTER: MarineGenomics Project

PROVIDER: E-GEOD-4580 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A dolphin peripheral blood leukocyte cDNA microarray for studies of immune function and stress reactions.

Mancia Annalaura A Lundqvist Mats L ML Romano Tracy A TA Peden-Adams Margie M MM Fair Patricia A PA Kindy Mark S MS Ellis Blake C BC Gattoni-Celli Sebastiano S McKillen David J DJ Trent Harold F HF Chen Yian Ann YA Almeida Jonas S JS Gross Paul S PS Chapman Robert W RW Warr Gregory W GW

Developmental and comparative immunology 20060920 5

A microarray focused on stress response and immune function genes of the bottlenosed dolphin has been developed. Random expressed sequence tags (ESTs) were isolated and sequenced from two dolphin peripheral blood leukocyte (PBL) cDNA libraries biased towards T- and B-cell gene expression by stimulation with IL-2 and LPS, respectively. A total of 2784 clones were sequenced and contig analysis yielded 1343 unigenes (archived and annotated at ). In addition, 52 dolphin genes known to be important i ...[more]

PMID: 17084893

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